https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Mechanisms of tethering and cargo transfer during epididymosome-sperm interactions https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:45249 Wed 26 Oct 2022 19:43:42 AEDT ]]> Mechanistic insight into the regulation of lipoxygenase-driven lipid peroxidation events in human spermatozoa and their impact on male fertility https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:45204 Wed 26 Oct 2022 15:29:09 AEDT ]]> Characteristics of the epididymal luminal environment responsible for sperm maturation and storage https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:34727 Wed 24 Jul 2024 12:26:16 AEST ]]> A novel role for milk fat globule-EGF factor 8 protein (MFGE8) in the mediation of mouse sperm–extracellular vesicle interactions https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:49349 Wed 17 Apr 2024 10:02:24 AEST ]]> The sins of our forefathers: paternal impacts on De Novo mutation rate and development https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:47168 Wed 14 Dec 2022 15:48:43 AEDT ]]> Significance of mitochondrial reactive oxygen species in the generation of oxidative stress in spermatozoa https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:4594 Wed 11 Apr 2018 14:21:05 AEST ]]> The lipid peroxidation product 4-hydroxynonenal contributes to oxidative stress-mediated deterioration of the ageing oocyte https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:30804 Wed 11 Apr 2018 12:10:05 AEST ]]> Mobile phone radiation induces reactive oxygen species production and DNA damage in human spermatozoa in vitro https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:7946 Wed 11 Apr 2018 10:00:06 AEST ]]> Proteomic analysis of koala (phascolarctos cinereus) spermatozoa and prostatic bodies https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:43968 Wed 05 Oct 2022 14:15:31 AEDT ]]> Pharmaco-proteogenomic profiling of pediatric diffuse midline glioma to inform future treatment strategies https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:47056 Tue 13 Dec 2022 15:32:40 AEDT ]]> Preclinical and clinical evaluation of German-sourced ONC201 for the treatment of H3K27M-mutant diffuse intrinsic pontine glioma https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:44354 Tue 11 Oct 2022 19:42:45 AEDT ]]> Probing the origins of 1,800 MHz radio frequency electromagnetic radiation induced damage in mouse immortalized germ cells and spermatozoa in vitro https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:35042 Tue 11 Jun 2019 14:20:01 AEST ]]> A Kinase Anchor Protein 4 is vulnerable to oxidative adduction in male germ cells https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:36571 Tue 09 Jun 2020 11:40:42 AEST ]]> Post-testicular sperm maturation in the saltwater crocodile Crocodylus porosus: assessing the temporal acquisition of sperm motility https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:39495 Crocodylus porosus as a tractable model for understanding crocodilian sperm physiology. In extending our systematic characterisation of saltwater crocodile spermatozoa, in this study we examined the development of motility during sperm transport through the excurrent duct system of the male crocodile. The results show that approximately 20% of crocodile testicular spermatozoa are immediately motile but experience a gradient of increasing motility (percentage motile and rate of movement) as they transit the male reproductive tract (epididymis). Moreover, we confirmed that, as in ejaculated crocodile spermatozoa, increased intracellular cAMP levels promoted a significant and sustained enhancement of sperm motility regardless of whether the cells were isolated from the testis or epididymis. Along with the development of artificial reproductive technologies, this research paves the way for the opportunistic recovery, storage and potential utilisation of post-mortem spermatozoa from genetically valuable animals.]]> Tue 09 Aug 2022 14:34:34 AEST ]]> Molecular insights into the divergence and diversity of post-testicular maturation strategies https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:40953 Tue 07 Nov 2023 09:51:49 AEDT ]]> Heat shock protein A2 (HSPA2): regulatory roles in germ cell development and sperm function https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:33498 Tue 06 Nov 2018 11:19:37 AEDT ]]> Characteristics of the epididymal luminal environment responsible for sperm maturation and storage https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:34015 Tue 03 Sep 2019 17:54:59 AEST ]]> Electromagnetic radiation and oxidative stress in the male germ line https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:23922 Tue 01 Nov 2016 10:15:52 AEDT ]]> Alterations in the p53 isoform ratio govern breast cancer cell fate in response to DNA damage https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:50644 Tue 01 Aug 2023 10:11:43 AEST ]]> Developmental expression of the dynamin family of mechanoenzymes in the mouse epididymis https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:34016 Thu 30 May 2019 15:47:52 AEST ]]> Characterization of a novel role for the dynamin mechanoenzymes in the regulation of human sperm acrosomal exocytosis https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:34014 Thu 30 May 2019 15:41:20 AEST ]]> The Impacts of Wireless Communication Electromagnetic Fields on Human Reproductive Biology https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:49642 Thu 25 May 2023 08:40:46 AEST ]]> Oxidative damage in naturally aged mouse oocytes is exacerbated by dysregulation of proteasomal activity https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:43344 Thu 15 Sep 2022 15:19:01 AEST ]]> Whole-body exposures to radiofrequency-electromagnetic energy can cause DNA damage in mouse spermatozoa via an oxidative mechanism https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:42690 Thu 01 Sep 2022 09:06:31 AEST ]]> Biological and clinical significance of DNA damage in the male germ line https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:7489 Sat 24 Mar 2018 10:46:10 AEDT ]]> DNA damage in human spermatozoa is highly correlated with the efficiency of chromatin remodeling and the formation of 8-hydroxy-2′-deoxyguanosine, a marker of oxidative stress https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:8206 Sat 24 Mar 2018 08:36:17 AEDT ]]> Analysis of the relationships between oxidative stress, DNA damage and sperm vitality in a patient population: development of diagnostic criteria https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:9572 Sat 24 Mar 2018 08:34:47 AEDT ]]> Cis-unsaturated fatty acids stimulate reactive oxygen species generation and lipid peroxidation in human spermatozoa https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:1079 Sat 24 Mar 2018 08:32:08 AEDT ]]> Definitive evidence for the nonmitochondrial production of superoxide anion by human spermatozoa https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:1163 Sat 24 Mar 2018 08:28:42 AEDT ]]> Metal complex-promoted cleavage of RNA dimers and trimers: electrospray ionisation mass spectrometry evidence for cleavage https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:1424 Sat 24 Mar 2018 08:28:14 AEDT ]]> New insights into sperm physiology and pathology https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:11318 Sat 24 Mar 2018 08:12:33 AEDT ]]> Sperm motility is lost in vitro as a consequence of mitochondrial free radical production and the generation of electrophilic aldehydes but can be significantly rescued by the presence of nucleophilic thiols https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:21182 Sat 24 Mar 2018 07:56:06 AEDT ]]> Assessment of the impact of direct in vitro PFAS treatment on mouse spermatozoa. https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:54975 Mon 25 Mar 2024 15:21:41 AEDT ]]> Heat exposure induces oxidative stress and DNA damage in the male germ line https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:47477 0.05). Collectively, our acute heat stress model supports the existence of heat susceptible stages of germ cell development, with the round spermatids being most perturbed and spermatogonial stem cells exhibiting resistance to this insult. Such findings were complemented by our chronic heat stress model, which further supported the vulnerability of the round spermatid population.]]> Mon 23 Jan 2023 11:33:24 AEDT ]]> The role of reactive oxygen species in acute myeloid leukaemia https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:38669 Mon 13 Dec 2021 16:34:15 AEDT ]]> (Z)-2-(3,4-dichlorophenyl)-3-(1H-pyrrol-2-yl)acrylonitrile exhibits selective antitumor activity in breast cancer cell lines via the aryl hydrocarbon receptor pathway https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:42808 Mon 05 Sep 2022 09:57:19 AEST ]]> Acrylamide modulates the mouse epididymal proteome to drive alterations in the sperm small non-coding RNA profile and dysregulate embryo development https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:40281 Fri 29 Jul 2022 13:23:12 AEST ]]> Assessment of the Emerging Threat Posed by Perfluoroalkyl and Polyfluoroalkyl Substances to Male Reproduction in Humans https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:45427 Fri 28 Oct 2022 11:48:22 AEDT ]]> New horizons in human sperm selection for assisted reproduction https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:51228 Fri 25 Aug 2023 11:51:38 AEST ]]> Good cop, bad cop: defining the roles of Δ40p53 in cancer and aging https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:40033 Fri 15 Jul 2022 10:11:14 AEST ]]> Glycerophospholipids protect stallion spermatozoa from oxidative damage in vitro https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:48890 Fri 14 Apr 2023 15:39:31 AEST ]]> Gross and microanatomy of the male reproductive duct system of the saltwater crocodile Crocodylus porosus https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:49362 Fri 12 May 2023 12:35:13 AEST ]]>